反応式
[N+:1]([C:4]1[CH:5]=[CH:6][C:7]([CH2:13][C:14]#[N:15])=[C:8]2[C:12]=1[NH:11][N:10]=[CH:9]2)([O-])=O>O1CCCC1.[Ni]>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]([CH2:13][C:14]#[N:15])=[C:8]2[C:12]=1[NH:11][N:10]=[CH:9]2参加物
4
実験手順
20.2 g of 2-(7-nitro-1H-indazol-4-yl)-acetonitrile in 750 ml of tetrahydrofuran is hydrogenated in the presence of 20.0 g of Raney nickel. The product is recrystallized from tetrahydrofuran/hexane, yielding 15.1 g of 2-(7-amino-1H-indazol-4-yl)acetonitrile, mp 164°-165° C.
後処理
- customThe product is recrystallized from tetrahydrofuran/hexane
出典と根拠
- ORDレコード
- ord-eb4a0d8baa674734875fca2f76128da7
- 出典データセット
- uspto-grants-1990_09
- 特許番号
- US04958026
関連ノート
読み込み中…