Water → Methyl (3-aminophenyl)carbamate
反応式
[Cl-].[NH4+].O.[CH3:4][O:5][C:6]([NH:8][C:9]1[CH:10]=[C:11]([N+:15]([O-])=O)[CH:12]=[CH:13][CH:14]=1)=[O:7]>[Fe].CC(O)C>[CH3:4][O:5][C:6]([NH:8][C:9]1[CH:10]=[C:11]([CH:12]=[CH:13][CH:14]=1)[NH2:15])=[O:7]参加物
6
実験手順
After refluxing a mixture of 37 g of iron powder, 1.9 g of ammonium chloride, 33 g of water, 13 g of 3-(methoxycarbonylamino)nitrobenzene, and 260 g of 2-propanol for 30 minutes, the reaction mixture was filtered under suction using sellaite. After extracting the product formed from the filtrate with ethyl acetate followed by washing with water, the product was dried by Glauber's salt. The solvent was distilled off from the product using an evaporator to provide 10.5 g (yield: 95%) of a black oily product.
後処理
- temperatureAfter refluxing
- filtrationthe reaction mixture was filtered under suction
- extractionAfter extracting the product
- customformed from the filtrate with ethyl acetate
- washby washing with water
- dry with materialthe product was dried by Glauber's salt
- distillationThe solvent was distilled off from the product
- customan evaporator
出典と根拠
- ORDレコード
- ord-559818628ca640d6b2a6ffe67d955ef0
- 出典データセット
- uspto-grants-1994_05
- 特許番号
- US05310634
反応ノート
読み込み中…