Acrylic Acid → Oxan-2-yl prop-2-enoate

HRID 1034127

反応式

HRID 1034127 の反応式
[C:1]([OH:5])(=[O:4])[CH:2]=[CH2:3].[O:6]1[CH:11]=[CH:10][CH2:9][CH2:8][CH2:7]1>ClCCl>[C:1]([O:5][CH:7]1[CH2:8][CH2:9][CH2:10][CH2:11][O:6]1)(=[O:4])[CH:2]=[CH2:3]

参加物

4

反応物 2

HCID 6581Acrylic AcidHCID 80803,4-dihydro-2H-pyran

生成物 1

HCID 21909470Oxan-2-yl prop-2-enoate収率 26%

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

A solution of 10.5 g (146 mmol, 10 ml) acrylic acid and 14.0 g (166 mmol, 15.2 ml) dihydropyran in 40 ml dichloromethane was stirred at room temperature for one day. The mixture was washed with saturated aqueous sodium bicarbonate and the organic layer was concentrated in vacuo. The residue was distilled to give 5.93 g (38.0 mmol, 26% yield) tetrahydropyran-2-yl acrylate, bp 40° C. at 0.2 torr.

後処理

  1. washThe mixture was washed with saturated aqueous sodium bicarbonate
  2. concentrationthe organic layer was concentrated in vacuo
  3. distillationThe residue was distilled

出典と根拠

ORDレコード
ord-1a9b6edd26bf4948b0ccb01a50c9bf06
出典データセット
uspto-grants-1994_05
特許番号
US05314785

関連ノート

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