Pyridine → (R)-tert-butyl 1-(5-bromo-3-(cyclopropanecarboxamido)-1H-pyrrolo[2,3-b]pyridin-4-yl)piperidin-3-yl(methyl)carbamate hydrochloride

反応式

[NH2:1][C:2]1[C:10]2[C:5](=[N:6][CH:7]=[C:8]([Br:26])[C:9]=2[N:11]2[CH2:16][CH2:15][CH2:14][C@@H:13]([N:17]([CH3:25])[C:18](=[O:24])[O:19][C:20]([CH3:23])([CH3:22])[CH3:21])[CH2:12]2)[NH:4][CH:3]=1.N1C=CC=CC=1.[CH:33]1([C:36]([Cl:38])=[O:37])[CH2:35][CH2:34]1.O[Li].O>CN1C(=O)CCC1.CCOC(C)=O.CC#N.O>[ClH:38].[Br:26][C:8]1[C:9]([N:11]2[CH2:16][CH2:15][CH2:14][C@@H:13]([N:17]([CH3:25])[C:18](=[O:24])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:12]2)=[C:10]2[C:2]([NH:1][C:36]([CH:33]3[CH2:35][CH2:34]3)=[O:37])=[CH:3][NH:4][C:5]2=[N:6][CH:7]=1