Thionyl Chloride → 4-Acetyl-1-naphthalenecarbonyl chloride
反応式
S(Cl)([Cl:3])=O.[C:5]([C:8]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[C:11]([C:18]([OH:20])=O)=[CH:10][CH:9]=1)(=[O:7])[CH3:6]>C1(C)C=CC=CC=1>[C:5]([C:8]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[C:11]([C:18]([Cl:3])=[O:20])=[CH:10][CH:9]=1)(=[O:7])[CH3:6]参加物
4
反応条件
- 温度
- 90 °C
実験手順
Thionyl chloride (35.00 g, 0.29 mol) was added to a solution of 4-acetyl-1-naphthalenecarboxylic acid (51.70 g, 0.24 mol) in toluene (350 mL). The mixture was warmed to 90° C. for 8.5 h. After cooling to 25° C., the solvent was removed under reduced pressure to give the title product as an off-white solid (55.1 g, 98.7% yield).
後処理
- temperatureAfter cooling to 25° C.
- customthe solvent was removed under reduced pressure
出典と根拠
- ORDレコード
- ord-8bec156b00c34eea82723611e18d3ad3
- 出典データセット
- uspto-grants-2013_10
- 特許番号
- US08546618B2
反応ノート
読み込み中…