Sodium Thiosulfate → Ubiquinol 10
反応式
[CH3:1][C:2]1[C:8](=[O:9])[C:7]([O:10][CH3:11])=[C:6]([O:12][CH3:13])[C:4](=[O:5])[C:3]=1[CH2:14]/[CH:15]=[C:16](/[CH2:18][CH2:19]/[CH:20]=[C:21](/[CH2:23]C/C=C(/CC/C=C(/CC/C=C(/CC/C=C(/CC/C=C(/CC/C=C(/CC/C=C(/CCC=C(C)C)\C)\C)\C)\C)\C)\C)\C)\[CH3:22])\[CH3:17].[O-]S([O-])(=S)=O.[Na+].[Na+]>CCCCCC>[CH3:1][C:2]1[C:8]([OH:9])=[C:7]([O:10][CH3:11])[C:6]([O:12][CH3:13])=[C:4]([OH:5])[C:3]=1[CH2:14]/[CH:15]=[C:16](/[CH2:18][CH2:19][CH:20]=[C:21]([CH3:23])[CH3:22])\[CH3:17]参加物
実験手順
30 g of ubiquinone (MW: 863.36) was dissolved in 300 ml of hexane. While the solution was stirred at room temperature, 300 ml of a 10% (w/v) sodium hyposulfite solution was poured to the solution. The mixture was stirred at room temperature for 2 hours. The mixture was all introduced into a separating funnel, and the hexane layer was collected. The remaining aqueous layer was then extracted twice each with 50 ml of hexane, and the extract was combined with the previously collected hexane layer. The hexane layer was washed six times each with 50 ml of a deaerated saturated saline solution, thereby obtaining a transparent hexane layer. After hexane was removed under a reduced pressure, nitrogen purging was performed for day and night, resulting in 29.5 g of a cream colored solid.
後処理
- stirringThe mixture was stirred at room temperature for 2 hours
- additionall introduced into a separating funnel
- customthe hexane layer was collected
- extractionThe remaining aqueous layer was then extracted twice each with 50 ml of hexane
- washThe hexane layer was washed six times each with 50 ml of a deaerated saturated saline solution
- customobtaining a transparent hexane layer
- customAfter hexane was removed under a reduced pressure, nitrogen purging
- waitwas performed for day and night
出典と根拠
- ORDレコード
- ord-096e7f8d2b224b6ca116216745fe6215
- 出典データセット
- uspto-grants-2013_10
- 特許番号
- US08551509B2
反応ノート
読み込み中…