HCID 178521700、化合物 → HCID 178507186、化合物
反応式
C(OC(=O)[NH:10][C:11]1([C:14]2[NH:18][N:17]=[N:16][N:15]=2)[CH2:13][CH2:12]1)C1C=CC=CC=1>CO.[Pd]>[NH:15]1[C:14]([C:11]2([NH2:10])[CH2:13][CH2:12]2)=[N:18][N:17]=[N:16]1参加物
4
実験手順
[1-(1H-tetrazol-5-yl)-cyclopropyl]-carbamic acid benzyl ester was dissolved in MeOH (5 ml). The solution was passed through a H-Cube hydrogenator at 0 bar, 30° C. and 1 ml/min with 10% Pd/C as a catalyst. The elute was concentrated to afford 48 mg of 1-(1H-tetrazol-5-yl)-cyclopropylamine as a solid product, m/z 126.5 [M+1]+.
後処理
- concentrationThe elute was concentrated
出典と根拠
- ORDレコード
- ord-1a589d74c5f941b19ed54273a8c12adf
- 出典データセット
- uspto-grants-2013_10
- 特許番号
- US08552205B2
反応ノート
読み込み中…