2-(Benzyloxy)-N,N-diethylacetamide → N,N-Diethyl-2-hydroxyacetamide

HRID 1041837ノート

反応式

HRID 1041837 の反応式
C([O:8][CH2:9][C:10]([N:12]([CH2:15][CH3:16])[CH2:13][CH3:14])=[O:11])C1C=CC=CC=1>C(OCC)(=O)C.[Pd]>[CH2:13]([N:12]([CH2:15][CH3:16])[C:10](=[O:11])[CH2:9][OH:8])[CH3:14]

参加物

4

反応物 1

HCID 606458502-(Benzyloxy)-N,N-diethylacetamide

生成物 1

HCID 4137580N,N-Diethyl-2-hydroxyacetamide

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 8857Ethyl Acetate溶媒

実験手順

2.20 g (9.9 mmol) of 2-(benzyloxy)-N,N-diethylacetamide were dissolved in 45 ml of ethyl acetate, and 200 mg of Pd/C (10%) were added. The reaction mixture was stirred under an atmosphere of hydrogen for 24 hours and then filtered through kieselguhr. The filtrate was evaporated to dryness, and N,N-diethyl-2-hydroxyacetamide was obtained as a colorless residue.

後処理

  1. filtrationfiltered through kieselguhr
  2. customThe filtrate was evaporated to dryness

出典と根拠

ORDレコード
ord-c4389c5a181347da859a63925e12a99d
出典データセット
uspto-grants-2013_10
特許番号
US08557741B2

反応ノート

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