Acetic acid, 2-(triphenylphosphoranylidene)-, methyl ester → 3-(2-Butoxy-4-trifluoromethyl-phenyl)-acrylic acid methyl ester
反応式
[CH2:1]([O:5][C:6]1[CH:13]=[C:12]([C:14]([F:17])([F:16])[F:15])[CH:11]=[CH:10][C:7]=1[CH:8]=O)[CH2:2][CH2:3][CH3:4].C1(P(=[CH:37][C:38]([O:40][CH3:41])=[O:39])(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1>CCOC(C)=O>[CH3:41][O:40][C:38](=[O:39])[CH:37]=[CH:8][C:7]1[CH:10]=[CH:11][C:12]([C:14]([F:17])([F:16])[F:15])=[CH:13][C:6]=1[O:5][CH2:1][CH2:2][CH2:3][CH3:4]参加物
4
実験手順
2-Butoxy-4-trifluoromethyl-benzaldehyde (420 mg) was reacted with methyl (triphenylphosphoranylidene)acetate (679 mg) at 110° C. overnight as described above to yield title compound (464 mg) after column chromatography (Hex/EtOAc=20/1).
出典と根拠
- ORDレコード
- ord-b8ab6c144cec439c9035284484b64a71
- 出典データセット
- uspto-grants-2013_10
- 特許番号
- US08557872B2
反応ノート
読み込み中…