Thionyl Chloride → 3-Nitro-5-(trifluoromethyl)benzoyl chloride
反応式
[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]=[C:11]([C:13]([F:16])([F:15])[F:14])[CH:12]=1)[C:7](O)=[O:8])([O-:3])=[O:2].S(Cl)([Cl:19])=O>>[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]=[C:11]([C:13]([F:16])([F:15])[F:14])[CH:12]=1)[C:7]([Cl:19])=[O:8])([O-:3])=[O:2]参加物
3
実験手順
A solution of thionyl chloride (30 ml) and 3-nitro-5-(trifluoromethyl)benzoic acid (10 g) was heated to reflux for 2 h. The reaction mixture was concentrated under reduced pressure and azeotroped with toluene (10 ml—removed under reduced pressure) to afford 3-nitro-5-(trifluoromethyl)benzoyl chloride.
後処理
- temperatureto reflux for 2 h
- concentrationThe reaction mixture was concentrated under reduced pressure
- customazeotroped with toluene (10 ml—removed under reduced pressure)
出典と根拠
- ORDレコード
- ord-8c96f968b55f49029bd9be4cd9d70eef
- 出典データセット
- uspto-grants-2013_10
- 特許番号
- US08557996B2
反応ノート
読み込み中…