Trifluoroacetic acid → HCID 178511287、化合物
反応式
[OH:1][C@H:2]1[CH2:7][CH2:6][C@H:5]([CH2:8][NH:9]C(=O)OC(C)(C)C)[CH2:4][CH2:3]1.FC(F)(F)C(O)=O>ClCCl>[NH2:9][CH2:8][C@H:5]1[CH2:6][CH2:7][C@H:2]([OH:1])[CH2:3][CH2:4]1参加物
4
実験手順
Tert-butyl trans-(4-hydroxycyclohexyl)methylcarbamate (1 g) in dichloromethane (10 ml) was treated with trifluoroacetic acid (10 ml) at 0° C. for two hours. The reaction mixture was concentrated and the residue was dried under vacuum to provide the title compound.
後処理
- concentrationThe reaction mixture was concentrated
- customthe residue was dried under vacuum
出典と根拠
- ORDレコード
- ord-4ed8e723af814e3db225f0828ed54856
- 出典データセット
- uspto-grants-2013_10
- 特許番号
- US08557983B2
反応ノート
読み込み中…