HCID 89685058、化合物 → [3-(2-Methyl-1,3-dioxolan-2-yl)phenyl]methanamine
反応式
[N:1]([CH2:4][C:5]1[CH:6]=[C:7]([C:11]2([CH3:16])[O:15][CH2:14][CH2:13][O:12]2)[CH:8]=[CH:9][CH:10]=1)=[N+]=[N-]>CO.[Pd]>[CH3:16][C:11]1([C:7]2[CH:6]=[C:5]([CH2:4][NH2:1])[CH:10]=[CH:9][CH:8]=2)[O:12][CH2:13][CH2:14][O:15]1参加物
4
実験手順
A mixture of the crude azide (194 mg, 0.88 mmol) in MeOH (5 mL) was hydrogenated in the presence of Pd/C (10%) at rt until completion of the reaction. The reaction mixture was filtered and concentrated under reduced pressure to give the title compound as a pale yellow solid. LC-MS-conditions 02: tR=0.59 min; [M+H]+=194.64.
後処理
- filtrationThe reaction mixture was filtered
- concentrationconcentrated under reduced pressure
出典と根拠
- ORDレコード
- ord-06cfe7fd07744a6c929b7b02d6f706e6
- 出典データセット
- uspto-grants-2013_10
- 特許番号
- US08563714B2
反応ノート
読み込み中…