Tetrahydrofuran → Methyl 3-(1,3-dioxoisoindolin-2-yl)-2-(thiophen-3-yl)propanoate

反応式

[Br:21][CH2:22][N:23]1[C:24](=[O:33])[c:25]2[c:26]([cH:29][cH:30][cH:31][cH:32]2)[C:27]1=[O:28].[CH2:34]1[O:35][CH2:36][CH2:37][CH2:38]1.[CH3:12][Si:13]([N-:14][Si:15]([CH3:16])([CH3:17])[CH3:18])([CH3:19])[CH3:20].[Li+:11].[s:1]1[cH:2][c:3]([CH2:6][C:7](=[O:8])[O:9][CH3:10])[cH:4][cH:5]1>>[s:1]1[cH:2][c:3]([CH:6]([C:7](=[O:8])[O:9][CH3:10])[CH2:22][N:23]2[C:24](=[O:33])[c:25]3[c:26]([cH:29][cH:30][cH:31][cH:32]3)[C:27]2=[O:28])[cH:4][cH:5]1