Aminoacetaldehyde dimethyl acetal → HCID 178495885、化合物

HRID 1046991

反応式

HRID 1046991 の反応式
[N:1]1[C:6]2[NH:7][C:8]3[CH:16]=[CH:15][CH:14]=[CH:13][C:9]=3[C:10](=S)[NH:11][C:5]=2[CH:4]=[CH:3][CH:2]=1.[CH3:17][O:18][CH:19]([O:22][CH3:23])[CH2:20][NH2:21]>>[CH3:17][O:18][CH:19]([O:22][CH3:23])[CH2:20][NH:21][C:10]1[C:9]2[CH:13]=[CH:14][CH:15]=[CH:16][C:8]=2[NH:7][C:6]2[N:1]=[CH:2][CH:3]=[CH:4][C:5]=2[N:11]=1

参加物

3

反応物 2

HCID 89728Aminoacetaldehyde dimethyl acetalHCID 454962295,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepine-6-thione

生成物 1

HCID 178495885HCID 178495885、化合物

反応条件

温度
95 °C

実験手順

A mixture of 5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepine-6-thione (3.21 g, 14 mmol) and 2,2-dimethoxyethylamine (7.6 mL, 70 mmol) was heated to 95° C. for 1 hour. After cooling to room temperature the solvent was evaporated in vacuo. The crude product was used in the next step without further purification.

後処理

  1. temperatureAfter cooling to room temperature the solvent
  2. customwas evaporated in vacuo
  3. customThe crude product was used in the next step without further purification

出典と根拠

ORDレコード
ord-1ddb5d730f7a48b5a2e2bc5cae496d22
出典データセット
uspto-grants-2013_10
特許番号
US08569331B2

関連ノート

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