Ammonium thiocyanate → HCID 117833541、化合物

反応式

[F:1][C:2]1[C:7]([F:8])=[C:6]([F:9])[C:5]([F:10])=[C:4]([F:11])[C:3]=1[C:12](=[O:15])[CH2:13]Br.[S-:16][C:17]#[N:18].[NH4+].C(=O)(O)[O-].[Na+]>C(#N)C>[F:1][C:2]1[C:7]([F:8])=[C:6]([F:9])[C:5]([F:10])=[C:4]([F:11])[C:3]=1[C:12](=[O:15])[CH2:13][S:16][C:17]#[N:18]

参加物

反応条件

温度: 25 °C

実験手順

A mixture of 1-(2,3,4,5,6-pentafluorophenyl)-2-bromo-1-ethanone 5.00 g, ammonium thiocyanate 1.58 g and acetonitrile 100 mL was stirred at 25° C. for one hour. To the reaction mixtures was added aqueous saturated sodium bicarbonate solution and the mixtures were extracted with ethyl acetate. The organic layers were washed with aqueous saturated sodium bicarbonate solution and were dried over anhydrous sodium sulfate. The resulting mixtures were concentrated under reduced pressure to give 1-(2,3,4,5,6-pentafluorophenyl)-2-thiocyanato-1-ethanone.