Triethylamine → HCID 178469368、化合物
反応式
C(N(CC)CC)C.Cl.[CH:9]([NH2:11])=[NH:10].[C:12]([C:19](OCC)=[O:20])#[C:13][C:14]([O:16][CH2:17][CH3:18])=[O:15]>C(#N)C>[OH:20][C:19]1[N:11]=[CH:9][N:10]=[C:13]([C:14]([O:16][CH2:17][CH3:18])=[O:15])[CH:12]=1参加物
5
反応条件
- 温度
- 50 °C
実験手順
Triethylamine (17.3 mL) was added dropwise to a solution of formamidine hydrochloride (10.0 g) and diethyl acetylenedicarboxylate (19.9 mL) in acetonitrile (300 mL) at room temperature. The reaction mixture was stirred at 50° C. for 1 hr and heated under reflux overnight. The solvent of the reaction mixture was evaporated under reduced pressure to give a crude product of the title compound as a brown solid. This compound was used for the next step without further purification.
後処理
- temperatureheated
- temperatureunder reflux overnight
- customThe solvent of the reaction mixture was evaporated under reduced pressure
出典と根拠
- ORDレコード
- ord-619edd9f62cc41ebac78a59eded74a31
- 出典データセット
- uspto-grants-2016_07
- 特許番号
- US09382188B2
反応ノート
読み込み中…