N-bromobutanimide → 2-Bromo-3-(bromomethyl)pyridine

HRID 1054039ノート

反応式

HRID 1054039 の反応式
[Br:1][C:2]1[C:7]([CH3:8])=[CH:6][CH:5]=[CH:4][N:3]=1.C1C(=O)N([Br:16])C(=O)C1>C(Cl)(Cl)(Cl)Cl>[Br:1][C:2]1[C:7]([CH2:8][Br:16])=[CH:6][CH:5]=[CH:4][N:3]=1

参加物

4

反応物 2

HCID 67184N-bromobutanimideHCID 2208322-Bromo-3-methylpyridine

生成物 1

HCID 109010782-Bromo-3-(bromomethyl)pyridine

試薬・触媒・溶媒 1

HCID 5943Carbon Tetrachloride溶媒

実験手順

Synthesized from 2-bromo-3-methylpyridine (5.00 g, 29.1 mmol), NBS (5.69 g, 32.0 mmol) and DBPO (352 mg, 1.46 mmol) in CCl4 according to Method A. Yield: 2.87 g, 11.4 mmol, 39%. This compound was directly used in the next step without further purification.

後処理

  1. customThis compound was directly used in the next step without further purification

出典と根拠

ORDレコード
ord-6d31b88bbc234e6da3ea61156b70d883
出典データセット
uspto-grants-2016_07
特許番号
US09394290B2

反応ノート

読み込み中…