1-((tert-Butoxycarbonyl)amino)cyclopropanecarboxylic acid → 1'H-spiro[cyclopropane-1,6'-pyrrolo[3,4-b]pyrrol]-4'(5'H)-one
反応式
[NH:1]1[CH:5]=[CH:4][C:3]2[C:6](=[O:9])[NH:7][CH2:8][C:2]1=2.[C:10](OC(NC1(C(O)=O)CC1)=O)(C)(C)[CH3:11]>>[NH:1]1[CH:5]=[CH:4][C:3]2[C:6](=[O:9])[NH:7][C:8]3([CH2:11][CH2:10]3)[C:2]1=2参加物
3
実験手順
This compound was prepared in a manner similar to that described for Intermediate 703, starting from 1-((tert-butoxycarbonyl)amino)cyclopropanecarboxylic acid. 1H NMR (400 MHz, DMSO-d6) δ ppm 11.08 (1H, br.), 7.53 (1H, s), 6.82 (1H, s), 6.11 (1H, d, J=2.2 Hz), 1.3 (2H, m), 1.27 (2H, m). m/z (ESI, +ve) 149.0 (M+H)+.
後処理
- customThis compound was prepared in a manner similar to
出典と根拠
- ORDレコード
- ord-6d1e86debddf41aca8f9154f7522e9de
- 出典データセット
- uspto-grants-2016_07
- 特許番号
- US09394297B2
反応ノート
読み込み中…