1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride → 9H-fluoren-9-ylmethyl N-[(2S)-1-[[(2S)-1-[[(E)-3-[(6aS)-3-[3-[[(6aS)-2-methoxy-6,11-dioxo-8-[(E)-prop-1-enyl]-5-(2-trimethylsilylethoxymethyl)-6a,7-dihydropyrrolo[2,1-c][1,4]benzodiazepin-3-yl]oxy]propoxy]-2-methoxy-6,11-dioxo-5-(2-trimethylsilylethoxymethyl)-6a,7-dihydropyrrolo[2,1-c][1,4]benzodiazepin-8-yl]prop-2-enyl]amino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]carbamate

反応式

Cl.C(N=C=NCCCN(C)C)C.[NH2:13][CH2:14]/[CH:15]=[CH:16]/[C:17]1[CH2:18][C@H:19]2[C:25](=[O:26])[N:24]([CH2:27][O:28][CH2:29][CH2:30][Si:31]([CH3:34])([CH3:33])[CH3:32])[C:23]3[CH:35]=[C:36]([O:41][CH2:42][CH2:43][CH2:44][O:45][C:46]4[C:47]([O:73][CH3:74])=[CH:48][C:49]5[C:55](=[O:56])[N:54]6[CH:57]=[C:58](/[CH:60]=[CH:61]/[CH3:62])[CH2:59][C@H:53]6[C:52](=[O:63])[N:51]([CH2:64][O:65][CH2:66][CH2:67][Si:68]([CH3:71])([CH3:70])[CH3:69])[C:50]=5[CH:72]=4)[C:37]([O:39][CH3:40])=[CH:38][C:22]=3[C:21](=[O:75])[N:20]2[CH:76]=1.[CH:77]1[C:89]2[CH:88]([CH2:90][O:91][C:92]([NH:94][C@@H:95]([CH:104]([CH3:106])[CH3:105])[C:96]([NH:98][C@@H:99]([CH3:103])[C:100](O)=[O:101])=[O:97])=[O:93])[C:87]3[C:82](=[CH:83][CH:84]=[CH:85][CH:86]=3)[C:81]=2[CH:80]=[CH:79][CH:78]=1>ClCCl>[CH3:40][O:39][C:37]1[C:36]([O:41][CH2:42][CH2:43][CH2:44][O:45][C:46]2[C:47]([O:73][CH3:74])=[CH:48][C:49]3[C:55](=[O:56])[N:54]4[CH:57]=[C:58](/[CH:60]=[CH:61]/[CH3:62])[CH2:59][C@H:53]4[C:52](=[O:63])[N:51]([CH2:64][O:65][CH2:66][CH2:67][Si:68]([CH3:71])([CH3:70])[CH3:69])[C:50]=3[CH:72]=2)=[CH:35][C:23]2[N:24]([CH2:27][O:28][CH2:29][CH2:30][Si:31]([CH3:34])([CH3:33])[CH3:32])[C:25](=[O:26])[C@@H:19]3[CH2:18][C:17](/[CH:16]=[CH:15]/[CH2:14][NH:13][C:100](=[O:101])[C@@H:99]([NH:98][C:96](=[O:97])[C@@H:95]([NH:94][C:92](=[O:93])[O:91][CH2:90][CH:88]4[C:89]5[CH:77]=[CH:78][CH:79]=[CH:80][C:81]=5[C:82]5[C:87]4=[CH:86][CH:85]=[CH:84][CH:83]=5)[CH:104]([CH3:106])[CH3:105])[CH3:103])=[CH:76][N:20]3[C:21](=[O:75])[C:22]=2[CH:38]=1