(R)-2-azido-1-benzylethylamine → (2R)-3-Phenylpropane-1,2-diamine

HRID 1057295

反応式

HRID 1057295 の反応式
[N:1]([CH2:4][C@H:5]([NH2:13])[CH2:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)=[N+]=[N-]>C(O)C.[Pd]>[NH2:1][CH2:4][C@H:5]([NH2:13])[CH2:6][C:7]1[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=1

参加物

4

反応物 1

HCID 14802497(R)-2-azido-1-benzylethylamine

生成物 1

HCID 12699299(2R)-3-Phenylpropane-1,2-diamine

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

A sample of the compound from step 4 (1.2 g, 6.8 mmol) is hydrogenated (4 atm) in ethanol over 1.2 g of 10% Pd/C for 21.5 hours at room temperature. The mixture is filtered to remove the catalyst, and the solvent is removed to afford the title compound.

後処理

  1. customfor 21.5 hours
  2. customat room temperature
  3. filtrationThe mixture is filtered
  4. customto remove the catalyst
  5. customthe solvent is removed

出典と根拠

ORDレコード
ord-0469f3e95c63410db270f6aafc3f1542
出典データセット
uspto-grants-2003_02
特許番号
US06514944B2

関連ノート

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