3-Phenylprop-2-Enal → HCID 18672287、化合物

反応式

[CH:1](=O)[CH:2]=[CH:3][C:4]1C=CC=C[CH:5]=1.[C:11]([C:16]1([C:23]([O:25][CH2:26][CH3:27])=[O:24])[C:20]([CH3:22])(C)[CH2:19][CH2:18][NH:17]1)([O:13][CH2:14][CH3:15])=[O:12]>>[CH2:26]([O:25][C:23]([C:16]1([C:11]([O:13][CH2:14][CH3:15])=[O:12])[CH:20]([C:22]2[CH:5]=[CH:4][CH:3]=[CH:2][CH:1]=2)[CH2:19][CH2:18][NH:17]1)=[O:24])[CH3:27]

参加物

反応物 2

HCID 3073-Phenylprop-2-Enal

HCID 21866189Diethyl 3,3-dimethylpyrrolidine-2,2-dicarboxylate

生成物 1

HCID 18672287HCID 18672287、化合物

実験手順

Diethyl-3-phenylpyrrolidine-2,2-dicarboxylate was prepared from cinnamaldehyde (1.22 mL, 9.70 mmol) essentially according to the procedure described in U.S. Pat. No. 4,060,603 for the preparation of 2,2-dicarboethoxy-3,3-dimethyl-pyrrolidine. The resulting yellow oil was used in the next step without purification. LCMS RT=1.26 min. LCMS (M+H)=292.1.

後処理

customThe resulting yellow oil was used in the next step without purification

出典と根拠

ORDレコード: ord-a1c9227759bf4afdbcc940b2717876f0
出典データセット: uspto-grants-2003_02
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06515011B2

反応ノート

読み込み中…

参加物