4-Hydroxybenzoic Acid → 4-(4-(Trifluoromethyl)phenoxy)benzoic acid

HRID 1058584

反応式

HRID 1058584 の反応式
[OH:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][CH:3]=1.[N+]([C:14]1[CH:19]=[CH:18][C:17]([C:20]([F:23])([F:22])[F:21])=[CH:16][CH:15]=1)([O-])=O.[H-].[Na+]>CN(C=O)C>[F:21][C:20]([F:23])([F:22])[C:17]1[CH:18]=[CH:19][C:14]([O:1][C:2]2[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][CH:3]=2)=[CH:15][CH:16]=1

参加物

5

反応物 3

HCID 1354-Hydroxybenzoic AcidHCID 9821P-NitrobenzotrifluorideHCID 24758Sodium hydride

生成物 1

HCID 36734814-(4-(Trifluoromethyl)phenoxy)benzoic acid

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide溶媒

実験手順

Following the general procedure of J. Polym. Sci., Polym. Chem. Ed. (1980), 18(10), 3069-80, 4-hydroxybenzoic acid, 4-nitro-1-(trifluoromethyl)benzene, and sodium hydride in DMF were heated at 130° C. to afford the title compound.

出典と根拠

ORDレコード
ord-72aa9766b9964a31bb7583d49c5faba1
出典データセット
uspto-grants-2003_02
特許番号
US06518267B1

関連ノート

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