(2E)-3-(furan-3-yl)prop-2-enoic acid → 3-(Oxolan-3-yl)propanoic acid

HRID 1058746ノート

反応式

HRID 1058746 の反応式
[O:1]1[CH:5]=[CH:4][C:3](/[CH:6]=[CH:7]/[C:8]([OH:10])=[O:9])=[CH:2]1.[H][H]>[Pd]>[O:1]1[CH2:5][CH2:4][CH:3]([CH2:6][CH2:7][C:8]([OH:10])=[O:9])[CH2:2]1

参加物

4

反応物 2

HCID 643403(2E)-3-(furan-3-yl)prop-2-enoic acidHCID 178418361HCID 178418361、化合物

生成物 1

HCID 2840903-(Oxolan-3-yl)propanoic acid

試薬・触媒・溶媒 1

HCID 23938Palladium触媒

実験手順

To a solution of trans-3-furanacrylic acid (10 g, 72.4 mmol) in industrial methylated spirits (50 mL) was added 10% palladium on carbon (1.0 g) at room temperature. The reaction vessel was charged with hydrogen gas to a pressure of 345 kPa and stirred at room temperature for 16 hours. The catalyst was removed by filtration and the filtrate was concentrated in vacuo to give the title compound as a colourless oil.

後処理

  1. customThe catalyst was removed by filtration
  2. concentrationthe filtrate was concentrated in vacuo

出典と根拠

ORDレコード
ord-6c863cb2aea242c3932cbfa3c441acd2
出典データセット
uspto-grants-2003_02
特許番号
US06518282B1

反応ノート

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