Potassium Nitrate → 4-Chloro-2-methoxy-5-nitrobenzoic acid
反応式
[Cl:1][C:2]1[CH:3]=[C:4]([O:11][CH3:12])[C:5](=[CH:9][CH:10]=1)[C:6]([OH:8])=[O:7].[N+:13]([O-])([O-:15])=[O:14].[K+]>S(=O)(=O)(O)O>[Cl:1][C:2]1[CH:3]=[C:4]([O:11][CH3:12])[C:5](=[CH:9][C:10]=1[N+:13]([O-:15])=[O:14])[C:6]([OH:8])=[O:7]参加物
4
実験手順
To a solution of 33 g of 4-chloro-o-anisic acid in sulfuric acid (100 ml) was added 20 g of potassium nitrate under ice-cooling and the resulting mixture was stirred for 2 hours. The reaction mixture was added to ice/water and extracted with ethyl acetate and the organic layer was dried over anhydrous magnesium sulfate. After distilling off the solvent under reduced pressure, 41 g of the title compound was obtained as pale yellow crystals.
後処理
- temperaturecooling
- extractionextracted with ethyl acetate
- dry with materialthe organic layer was dried over anhydrous magnesium sulfate
- distillationAfter distilling off the solvent under reduced pressure
出典と根拠
- ORDレコード
- ord-4358da7dcdd84af1b779e44316c8ec0a
- 出典データセット
- uspto-grants-2003_02
- 特許番号
- US06518423B1
反応ノート
読み込み中…