2-Amino-4-Nitrophenol → HCID 18629909、化合物
反応式
Cl.[C:2]([CH2:4][C:5](=[NH:8])[O:6][CH3:7])#[N:3].[N+:9]([C:12]1[CH:17]=C[C:15](O)=[C:14](N)[CH:13]=1)([O-:11])=[O:10]>CO>[N+:9]([C:12]1[C:17]2[N:8]=[C:5]([CH2:4][C:2]#[N:3])[O:6][C:7]=2[CH:15]=[CH:14][CH:13]=1)([O-:11])=[O:10]参加物
4
実験手順
The mixture of methyl cyanoacetimidate hydrochloride (43.47 g, 0.32 mole) and 4-nitro-2-aminophenol (24.9 g, 0.16 mole) in methanol (260 ml) was heated at reflux for 3 h. The mixture was placed in an ice bath for 30 minutes and was filtered. The solid material was suspended in water (300 ml), stirred for a few minutes and filtered. It was washed with water (200 ml) and air dried to give 4-nitro-2-benzoxazoleacetonitrile (27.38 g, 83%).
後処理
- temperaturewas heated
- temperatureat reflux for 3 h
- filtrationwas filtered
- filtrationfiltered
- washIt was washed with water (200 ml) and air
- customdried
出典と根拠
- ORDレコード
- ord-433be1a8d98d4bf698b3f36f7c2ddc37
- 出典データセット
- uspto-grants-2003_02
- 特許番号
- US06521397B1
反応ノート
読み込み中…