3-(3-Trifluoromethylpyridin-2-yl)nitrobenzene → HCID 18631012、化合物
反応式
[F:1][C:2]([F:19])([F:18])[C:3]1[C:4]([C:9]2[CH:10]=[C:11]([N+:15]([O-])=O)[CH:12]=[CH:13][CH:14]=2)=[N:5][CH:6]=[CH:7][CH:8]=1>C(O)C.[Pd]>[F:19][C:2]([F:1])([F:18])[C:3]1[C:4]([C:9]2[CH:10]=[C:11]([CH:12]=[CH:13][CH:14]=2)[NH2:15])=[N:5][CH:6]=[CH:7][CH:8]=1参加物
4
実験手順
A suspension of 3-(3-trifluoromethylpyridin-2-yl)nitrobenzene (500 mg) in ethanol (10 ml) was hydrogenated over palladium on carbon (10% w/w, 50% wet, 167 mg) under a hydrogen atmosphere for 2 hours. The catalyst was filtered off, and the filtrate was evaporated under reduced pressure to give 3-(3-trifluoromethylpyridin-2-yl)aniline (425 mg).
後処理
- filtrationThe catalyst was filtered off
- customthe filtrate was evaporated under reduced pressure
出典と根拠
- ORDレコード
- ord-8facb9c335e74fc6a195e8f2f741e7fc
- 出典データセット
- uspto-grants-2003_02
- 特許番号
- US06521643B1
反応ノート
読み込み中…