3-(4-Ethoxypyridin-2-yl)nitrobenzene → 3-(4-Ethoxypyridin-2-yl)aniline

HRID 1059933ノート

反応式

HRID 1059933 の反応式
[CH2:1]([O:3][C:4]1[CH:9]=[CH:8][N:7]=[C:6]([C:10]2[CH:11]=[C:12]([N+:16]([O-])=O)[CH:13]=[CH:14][CH:15]=2)[CH:5]=1)[CH3:2]>C(O)C.[Pd]>[CH2:1]([O:3][C:4]1[CH:9]=[CH:8][N:7]=[C:6]([C:10]2[CH:11]=[C:12]([CH:13]=[CH:14][CH:15]=2)[NH2:16])[CH:5]=1)[CH3:2]

参加物

4

反応物 1

HCID 186675793-(4-Ethoxypyridin-2-yl)nitrobenzene

生成物 1

HCID 186676293-(4-Ethoxypyridin-2-yl)aniline収率 100.3%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

A suspension of 3-(4-ethoxypyridin-2-yl)nitrobenzene (0.3 g) in ethanol (6 ml) was hydrogenated over palladium on carbon (10% w/w, 50% wet, 0.2 g) under a hydrogen atmosphere for 3 hours. The catalyst was filtered off, and the filtrate was evaporated under reduced pressure to give 3-(4-ethoxypyridin-2-yl)aniline (0.264 g).

後処理

  1. filtrationThe catalyst was filtered off
  2. customthe filtrate was evaporated under reduced pressure

出典と根拠

ORDレコード
ord-3835b13a896b4ea49d3c9b17e10c2f25
出典データセット
uspto-grants-2003_02
特許番号
US06521643B1

反応ノート

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