Water → HCID 22283025、化合物
反応式
[CH3:1][O:2][C:3]1[C:8]2[N:9]=[C:10]([NH:12]C(=O)O)[S:11][C:7]=2[C:6]([CH:16]=[CH2:17])=[CH:5][CH:4]=1.O>C(O)CO>[CH3:1][O:2][C:3]1[C:8]2[N:9]=[C:10]([NH2:12])[S:11][C:7]=2[C:6]([CH:16]=[CH2:17])=[CH:5][CH:4]=1参加物
4
反応条件
- 温度
- 100 °C
実験手順
(4-Methoxy-7-vinyl-benzothiazol-2-yl)-carbamic acid methyll ester was dissolved in ethylenglycol/2N KOH (2:1) and stirred at 100° C. for 3 hrs. Then water was added and the mixture was extracted with CH2Cl2, the organic phase was washed with brine and dried over MgSO4. After evaporation the residue was crystallized from CH2Cl2. White crystals (64%); F.p.: 155-159° C.
後処理
- extractionthe mixture was extracted with CH2Cl2
- washthe organic phase was washed with brine
- dry with materialdried over MgSO4
- customAfter evaporation the residue
- customwas crystallized from CH2Cl2
- custom155-159° C.
出典と根拠
- ORDレコード
- ord-5d9d853d8ebb429aae92605a7c289c71
- 出典データセット
- uspto-grants-2003_02
- 特許番号
- US06521754B2
反応ノート
読み込み中…