2,5-Dibromohydroquinone → 2,5-Dibromo-1,4-benzoquinone

HRID 1060618ノート

反応式

HRID 1060618 の反応式
[Br:1][C:2]1[CH:8]=[C:7]([OH:9])[C:6]([Br:10])=[CH:5][C:3]=1[OH:4].[N+]([O-])([O-])=O.[NH4+].[Ce]>C(#N)C.O>[Br:1][C:2]1[C:3](=[O:4])[CH:5]=[C:6]([Br:10])[C:7](=[O:9])[CH:8]=1

参加物

5

反応物 2

HCID 2809452,5-DibromohydroquinoneHCID 57418452Ammonium cerium-nitrate

生成物 1

HCID 5430932,5-Dibromo-1,4-benzoquinone収率 71%

試薬・触媒・溶媒 2

HCID 962Water溶媒HCID 6342Acetonitrile溶媒

実験手順

To a solution of 2,5-dibromohydroquinone (1) (5 g, 18.6 mol) in acetonitrile (250 ml) was added cerium ammonium nitrate (21.4 g, 39.0 mmol), in small portions. The clear orange solution was stirred for 10 min at room temperature, diluted with water (80 ml) and extracted with chloroform (3×200 ml). The combined chloroform layers were dried over sodium sulphate and evaporated, yielding 3.5 g (71%) of the quinone (2).

後処理

  1. extractionextracted with chloroform (3×200 ml)
  2. dry with materialThe combined chloroform layers were dried over sodium sulphate
  3. customevaporated

出典と根拠

ORDレコード
ord-58327378666747f79ea504e3e98fc7d5
出典データセット
uspto-grants-2003_02
特許番号
US06525063B2

反応ノート

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