3-Ethoxy-4-nitrobenzoic acid → 4-Amino-3-ethoxybenzoic acid

HRID 1060824

反応式

HRID 1060824 の反応式
[CH2:1]([O:3][C:4]1[CH:5]=[C:6]([CH:10]=[CH:11][C:12]=1[N+:13]([O-])=O)[C:7]([OH:9])=[O:8])[CH3:2]>[Pd]>[NH2:13][C:12]1[CH:11]=[CH:10][C:6]([C:7]([OH:9])=[O:8])=[CH:5][C:4]=1[O:3][CH2:1][CH3:2]

参加物

3

反応物 1

HCID 223975093-Ethoxy-4-nitrobenzoic acid

生成物 1

HCID 223974484-Amino-3-ethoxybenzoic acid収率 92.1%

試薬・触媒・溶媒 1

HCID 23938Palladium触媒

実験手順

3-Ethoxy-4-nitrobenzoic acid (0.31 g) was treated with 5% palladium on charcoal under an atmosphere of hydrogen (1 bar) for 3 hours. The reaction mixture was filtered and the filtrate was evaporated to leave the product as a beige solid (0.245 g; MS: ES− (M-H) 180).

後処理

  1. filtrationThe reaction mixture was filtered
  2. customthe filtrate was evaporated

出典と根拠

ORDレコード
ord-6030d1e15c2643c79bc1c31082b9bb2a
出典データセット
uspto-grants-2003_02
特許番号
US06525070B2

関連ノート

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