HCID 12899697、化合物 → HCID 20277153、化合物
反応式
[CH:1]12[CH2:7][CH:4]([CH:5]=[CH:6]1)[CH2:3][CH:2]2[CH2:8][N:9]1[CH:13]=[CH:12][N:11]=[CH:10]1.[H][H]>[Pd].C(O)C>[CH:1]12[CH2:7][CH:4]([CH2:5][CH2:6]1)[CH2:3][CH:2]2[CH2:8][N:9]1[CH:13]=[CH:12][N:11]=[CH:10]1参加物
5
実験手順
A mixture of 1-(bicyclo[2.2.1]hept-5-en-2-ylmethyl)imidazole (2.0 g, 11.48 mmol) and palladium on charcoal (0.2 g, 10%) in dry ethanol was shaken in an atmosphere of hydrogen for 4.5 h. The reaction mixture was then filtered through Hyflo-Supercel, and the filtrate was concentrated under reduced pressure to afford a colourless oil. Distillation of the oil afforded 1-(bicyclo[2.2.1]heptan-2-ylmethyl)imidazole as a colourless oil, b.p. 82°-84°/0.15 mm Hg.
後処理
- filtrationThe reaction mixture was then filtered through Hyflo-Supercel
- concentrationthe filtrate was concentrated under reduced pressure
- customto afford a colourless oil
- distillationDistillation of the oil
出典と根拠
- ORDレコード
- ord-444a0b7921a8422b93ebb71b6ecfcb52
- 出典データセット
- uspto-grants-1982_05
- 特許番号
- US04328234
反応ノート
読み込み中…