化工社化工社 化学情報印刷レポート · 研究参考用
Acetic Acid → [1-(p-Nitrophenyl)-1H-1,2,4-triazol-5-yl]pyrazine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetic Acid | HCID 176 | — |
| 反応物 | (4-Nitrophenyl)hydrazine | HCID 3310889 | — |
| 反応物 | N-[(Dimethylamino)methylene]pyrazine-2-carboxamide | HCID 16727655 | — |
| 溶媒 | 1,4-Dioxane | HCID 31275 | — |
| 生成物 | [1-(p-Nitrophenyl)-1H-1,2,4-triazol-5-yl]pyrazine | HCID 12850299 | — |
反応手順
A 10.0 g. portion of N-(dimethylaminomethylene)pyrazine carboxamide is added to a mixture of 10.3 g. of 4-nitrophenylhydrazine, 200 ml. of acetic acid and 50 ml. of p-dioxane. The mixture is heated at 90° for 5 hours and evaporated to dryness in vacuo. The residue is recrystallized from ethanol giving 9.0 g. of the desired product as tan crystals, mp. 188°-189° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04329463 |
| 出典データセット | uspto-grants-1982_05 |
| ORD ID | ord-fc6357455ad44e8aa71868f8539e7e91 |
| 出典メモ | uspto-grants-1982_05 |