Sodium hydride → N,N-Dimethyl-3-phenyl-3-(2-pyrazinyloxy)propylamine

HRID 1065635

反応式

HRID 1065635 の反応式
[CH3:1][N:2]([CH2:4][CH2:5][CH:6]([OH:13])[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)[CH3:3].[H-].[Na+].Cl[C:17]1[CH:22]=[N:21][CH:20]=[CH:19][N:18]=1>CS(C)=O>[CH3:1][N:2]([CH2:4][CH2:5][CH:6]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)[O:13][C:17]1[CH:22]=[N:21][CH:20]=[CH:19][N:18]=1)[CH3:3]

参加物

5

反応物 3

HCID 24758Sodium hydrideHCID 73277ChloropyrazineHCID 1106653-(Dimethylamino)-1-phenylpropan-1-ol

生成物 1

HCID 20539675N,N-Dimethyl-3-phenyl-3-(2-pyrazinyloxy)propylamine

試薬・触媒・溶媒 1

HCID 679Dimethyl Sulfoxide溶媒

実験手順

Following the method of Example 3, reaction of N,N-dimethyl-3-hydroxy-3-phenylpropylamine, sodium hydride and 2-chloropyrazine in DMSO gives the title compound.

出典と根拠

ORDレコード
ord-b4ab8759186d463685d80bf1bfce45dd
出典データセット
uspto-grants-1982_05
特許番号
US04330546

関連ノート

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