Sodium Hydroxide → HCID 20539740、化合物
反応式
C([O:3][C:4](=[O:22])[C:5]([NH:7][C:8]1[CH:16]=[CH:15][C:14]([CH3:17])=[C:13]2[C:9]=1[C:10](=[O:21])[CH2:11][CH:12]2[CH2:18][CH2:19][CH3:20])=[O:6])C.[OH-].[Na+]>CO>[CH3:17][C:14]1[CH:15]=[CH:16][C:8]([NH:7][C:5](=[O:6])[C:4]([OH:22])=[O:3])=[C:9]2[C:13]=1[CH:12]([CH2:18][CH2:19][CH3:20])[CH2:11][C:10]2=[O:21]参加物
4
実験手順
A solution of 1.6 g N-(7-methyl-3-oxo-1-propyl-4-indanyl)oxamic acid ethyl ester in 100 ml methanol is heated at reflux with 5.28 ml of 1 M aqueous NaOH for 30 minutes. The solution is concentrated, diluted with water, filtered through a filtering aid such as Hyflo (Registered Trade Mark), and made acid with 2 N HCL. The title compound is filtered off and dried. M.Pt. 157°-158°.
後処理
- concentrationThe solution is concentrated
- additiondiluted with water
- filtrationfiltered through a filtering aid such as Hyflo (Registered Trade Mark)
- filtrationThe title compound is filtered off
- customdried
出典と根拠
- ORDレコード
- ord-c022c94bab7342eeac70a3671c3f5fa2
- 出典データセット
- uspto-grants-1982_05
- 特許番号
- US04330555
反応ノート
読み込み中…