Acetonitrile → 2-(3-(1-Chloro-8-methoxy-2,7-naphthyridin-3-yl)propyl)isoindoline-1,3-dione

反応式

[CH3:1][O:2][c:3]1[n:4][cH:5][cH:6][c:7]2[cH:8][c:9]([CH2:14][CH2:15][CH2:16][N:17]3[C:18](=[O:27])[c:19]4[cH:20][cH:21][cH:22][cH:23][c:24]4[C:25]3=[O:26])[nH:10][c:11](=[O:13])[c:12]12.[CH3:33][C:34]#[N:35].[P:28]([Cl:29])([Cl:30])([Cl:31])=[O:32]>>[CH3:1][O:2][c:3]1[n:4][cH:5][cH:6][c:7]2[cH:8][c:9]([CH2:14][CH2:15][CH2:16][N:17]3[C:18](=[O:27])[c:19]4[cH:20][cH:21][cH:22][cH:23][c:24]4[C:25]3=[O:26])[n:10][c:11]([Cl:30])[c:12]12

参加物

反応物 3

HCID 6342Acetonitrile

HCID 24813Phosphorus oxychloride

HCID 580946292-(3-(8-Methoxy-1-oxo-1,2-dihydro-2,7-naphthyridin-3-yl)propyl)isoindoline-1,3-dione

生成物 1

HCID 580936562-(3-(1-Chloro-8-methoxy-2,7-naphthyridin-3-yl)propyl)isoindoline-1,3-dione

出典と根拠

ORDレコード: ord-362f688c5dec44c29a22242e257d6a74
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…