Sorbitan mono-(9Z)-9-octadecenoate → glycerol ascorbic acid Span 80

HRID 1066707

反応式

HRID 1066707 の反応式
[O:1]=[C:2]1O[C@H]([C@H](CO)O)[C:5]([OH:6])=[C:3]1[OH:4].[O:13]=[C:14]1[O:20][C@H:19]([C@H:21]([CH2:23][OH:24])[OH:22])[C:17]([OH:18])=[C:15]1[OH:16].OCC(CO)O.[CH3:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38]/[CH:39]=[CH:40]\[CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][C:48]([O:50][CH2:51][C@@H:52]([OH:60])[C@H:53]1[O:57][CH2:56][C@H:55]([OH:58])[C@H:54]1[OH:59])=[O:49]>OCC(CO)O>[OH:1][CH2:2][CH:3]([CH2:5][OH:6])[OH:4].[O:13]=[C:14]1[O:20][C@H:19]([C@H:21]([CH2:23][OH:24])[OH:22])[C:17]([OH:18])=[C:15]1[OH:16].[CH3:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38]/[CH:39]=[CH:40]\[CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][C:48]([O:50][CH2:51][C@@H:52]([OH:60])[C@H:53]1[O:57][CH2:56][C@H:55]([OH:58])[C@H:54]1[OH:59])=[O:49]

参加物

5

反応物 3

HCID 9920342Sorbitan mono-(9Z)-9-octadecenoateHCID 54670067L-Ascorbic AcidHCID 131722625Ascorbic acid glycerol2 回

生成物 1

HCID 131722624glycerol ascorbic acid Span 80

試薬・触媒・溶媒 1

HCID 753Glycerol溶媒

実験手順

L-Ascorbic acid (50 mg) was dissolved in a 1 mL glycerol solution by heating and stirring the mixture. After being cooled to room temperature, the ascorbic acid/glycerol solution was mixed with GCSF powder (45.3 mg) and Span 80 (250 mL). 3.75 mL thickened oil (3% AIMS) prepared as described above was added to the G-CSF/ascorbic acid/glycerol mixture and ground together to give a viscous oil suspension (G-CSF/20% glycerol+ascorbic acid/Span 80/3% AIMS/oil).

後処理

  1. temperatureby heating

出典と根拠

ORDレコード
ord-ac8f2f07d82e4924bd96664d332a8bca
出典データセット
uspto-grants-2001_06
特許番号
US06245740B1

関連ノート

読み込み中…