1-Piperidinamine, N,N-dimethyl- → HCID 54146532、化合物
反応式
CN([N:4]1[CH2:9][CH2:8][CH2:7][CH2:6][CH2:5]1)C.[Cl:10][C:11]1[CH:33]=[CH:32][C:14]([O:15][CH2:16][C:17]2[N:18]([CH3:31])[C:19]3[C:24]([C:25]=2[CH:26]=[CH:27][C:28](O)=[O:29])=[CH:23][CH:22]=[CH:21][CH:20]=3)=[CH:13][CH:12]=1.Cl.[CH3:35][N:36](C)[CH2:37]CCN=C=NCC>C(Cl)Cl>[Cl:10][C:11]1[CH:33]=[CH:32][C:14]([O:15][CH2:16][C:17]2[N:18]([CH3:31])[C:19]3[C:24]([C:25]=2[CH:26]=[CH:27][C:28]([N:4]2[CH2:5][CH2:6][CH:7]([N:36]([CH3:37])[CH3:35])[CH2:8][CH2:9]2)=[O:29])=[CH:23][CH:22]=[CH:21][CH:20]=3)=[CH:13][CH:12]=1参加物
5
実験手順
Under a nitrogen atmosphere dimethylaminopiperidine was dissolved in 3.0 ml of methylene chloride. To this solution were added 3-(2-[(4-chlorophenoxy)methyl]-1-methyl-1H-indol-3-yl]prop-2-enoic acid (0.050 g, 0.1462 mmol) and 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (0.0356 g, 0.278 mmol). The resulting mixture was stirred at room temperature overnight.