1-Acetoxy-2-[(3,4-methylenedioxy)-6-nitrophenyl]ethane → 1-Acetoxy-2-[(3,4-methylenedioxy)-6-aminophenyl]ethane

HRID 1067644ノート

反応式

HRID 1067644 の反応式
[C:1]([O:4][CH2:5][CH2:6][C:7]1[C:12]([N+:13]([O-])=O)=[CH:11][C:10]2[O:16][CH2:17][O:18][C:9]=2[CH:8]=1)(=[O:3])[CH3:2]>C(OCC)(=O)C.[Pd]>[C:1]([O:4][CH2:5][CH2:6][C:7]1[C:12]([NH2:13])=[CH:11][C:10]2[O:16][CH2:17][O:18][C:9]=2[CH:8]=1)(=[O:3])[CH3:2]

参加物

4

反応物 1

HCID 234454281-Acetoxy-2-[(3,4-methylenedioxy)-6-nitrophenyl]ethane

生成物 1

HCID 234452401-Acetoxy-2-[(3,4-methylenedioxy)-6-aminophenyl]ethane収率 98.8%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 8857Ethyl Acetate溶媒

実験手順

The solution of 1-acetoxy-2-[(3,4-methylenedioxy)-6-nitrophenyl]ethane (0.8 g, 3.13 mmol) in ethyl acetate (25 mL) was subjected to catalytic hydrogenation using 10% palladium on carbon (100 mg) at 50 psi for 30 min. The catalyst was filtered and the solvent was removed under reduced pressure to give 1-acetoxy-2-[(3,4-methylenedioxy)-6-aminophenyl]ethane as a solid (0.69 g, 98% yield).

後処理

  1. customfor 30 min
  2. filtrationThe catalyst was filtered
  3. customthe solvent was removed under reduced pressure

出典と根拠

ORDレコード
ord-a9a3c734fb3347b3882f7ba5991940bc
出典データセット
uspto-grants-2001_06
特許番号
US06248767B1

反応ノート

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