Water → Cyclopentadienyl-2-indenyl-dimethylsilane

HRID 1068059ノート

反応式

HRID 1068059 の反応式
Cl[Si:2]([C:5]1[CH2:6][C:7]2[C:12]([CH:13]=1)=[CH:11][CH:10]=[CH:9][CH:8]=2)([CH3:4])[CH3:3].[CH:14]1([Na])[CH:18]=[CH:17][CH:16]=[CH:15]1.O>C(OCC)C.O1CCCC1>[CH:14]1([Si:2]([C:5]2[CH2:6][C:7]3[C:12]([CH:13]=2)=[CH:11][CH:10]=[CH:9][CH:8]=3)([CH3:3])[CH3:4])[CH:18]=[CH:17][CH:16]=[CH:15]1

参加物

6

反応物 3

HCID 962WaterHCID 22395124Chloro(1H-inden-2-yl)dimethylsilaneHCID 178507085HCID 178507085、化合物

生成物 1

HCID 131722676Cyclopentadienyl-2-indenyl-dimethylsilane収率 46%

試薬・触媒・溶媒 2

HCID 3283Diethyl Ether溶媒HCID 8028Tetrahydrofuran溶媒

反応条件

温度
0 °C

実験手順

Chloro-2-indenyldimethylsilane (4.6 g, 0.022 mol.) from Example 1 was dissolved in 20 ml of diethyl ether. The solution was cooled to 0° C., and a solution of cyclopentadienylsodium (1.94 g, 0.022 mol.) in 20 ml of tetrahydrofuran was added dropwise. The mixture was stirred for 15 hours at 25° C. 50 ml of water were then added, and the organic phase was washed with water again and dried over Na2SO4. After removal of the solvents under an oil pump vacuum, the light-yellow oil that remained was purified by means of column chromatography. The solvent was removed to yield 2.4 g (46%) of cyclopentadienyl-2-indenyl-dimethylsilane in the form of a colorless oil.

後処理

  1. washthe organic phase was washed with water again
  2. dry with materialdried over Na2SO4
  3. customAfter removal of the solvents under an oil pump vacuum
  4. customthe light-yellow oil that remained was purified by means of column chromatography
  5. customThe solvent was removed

出典と根拠

ORDレコード
ord-197e2ae0a8af487e9547da2006281190
出典データセット
uspto-grants-2001_06
特許番号
US06248912B1

反応ノート

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