Sodium hydride → 2-(2-Chloroethyl)-5-phenyl-1,2,5-thiadiazolidine-1,1-dioxide
反応式
[Cl:1][CH2:2][CH2:3][N:4]([CH2:15][CH2:16]Cl)[S:5]([NH:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)(=[O:7])=[O:6].[H-].[Na+]>CN(C=O)C>[Cl:1][CH2:2][CH2:3][N:4]1[CH2:15][CH2:16][N:8]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[S:5]1(=[O:7])=[O:6]参加物
4
実験手順
Using a slow dropper, a solution of 12.6 g of the product obtained in Step 2 above in 25 ml of DMF is introduced onto a suspension of 1.4 g of NaH in 175 ml of DMF and stirring is carried out for 12 hours. The reaction mixture is then poured onto ice in order to bring about crystallisation of the expected product.
後処理
- additionThe reaction mixture is then poured onto ice in order
- customto bring about crystallisation of the expected product
出典と根拠
- ORDレコード
- ord-e61c6097449945a5b4893cc191ef74b1
- 出典データセット
- uspto-grants-2005_06
- 特許番号
- US06903103B2
反応ノート
読み込み中…