2-Dimethylaminopyridine → 2,4-Dichloro-6-methyloxybenzoyl chloride
反応式
[Cl:1][C:2]1[CH:10]=[C:9]([Cl:11])[CH:8]=[C:7]([O:12][CH3:13])[C:3]=1[C:4](O)=[O:5].CN(C1C=CC=CN=1)C.S(Cl)([Cl:25])=O>C(Cl)Cl>[Cl:1][C:2]1[CH:10]=[C:9]([Cl:11])[CH:8]=[C:7]([O:12][CH3:13])[C:3]=1[C:4]([Cl:25])=[O:5]参加物
5
実験手順
26.0 g. (0.117 mol) 2,4-Dichloro-6-methoxybenzoic acid were dissolved in 50 ml. anhydrous methylene chloride and, after the addition of 0.1 g. dimethylaminopyridine, 50 ml. thionyl chloride were added dropwise thereto at ambient temperature. After stirring for 15 hours, the reaction mixture was evaporated and the residue distilled. Yield: 55% of theory; b.p. 118-124° C./0.1 mm.Hg.
後処理
- customat ambient temperature
- customthe reaction mixture was evaporated
- distillationthe residue distilled
出典と根拠
- ORDレコード
- ord-54c91ab192824b9c8107ede9611926c7
- 出典データセット
- uspto-grants-1990_11
- 特許番号
- US04970077
反応ノート
読み込み中…