Phosphoric Acid → 4-Hydroxy-4-methyl-5-(prop-2-en-1-yl)cyclopent-2-en-1-one

HRID 1073695ノート

反応式

HRID 1073695 の反応式
[CH3:1][C:2]1[O:11][C:5]([CH:6](O)[CH2:7][CH:8]=[CH2:9])=[CH:4][CH:3]=1.P([O-])([O-])(O)=[O:13].[K+].[K+].P(=O)(O)(O)O>O>[CH2:7]([CH:6]1[C:2]([OH:11])([CH3:1])[CH:3]=[CH:4][C:5]1=[O:13])[CH:8]=[CH2:9]

参加物

5

反応物 3

HCID 1004Phosphoric AcidHCID 24450Potassium Phosphate, DibasicHCID 110625572-(1-hydroxy-3-butenyl)-5-methyl furan

生成物 1

HCID 128798724-Hydroxy-4-methyl-5-(prop-2-en-1-yl)cyclopent-2-en-1-one収率 80%

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

In the same apparatus as in Example 1, 5-methyl-allyl-furfuryl alcohol (50 parts) and a buffer solution prepared from water (1500 parts) and dipotassium monohydrogen phosphate (1.7 parts) and adjusted to pH 5.1 with phosphoric acid were charged, and the resultant mixture was stirred at 100° C. in a nitrogen stream until the starting compound was consumed. The reaction mixture was treated as in Example 1 to give 2-allyl-3-hydroxy-3-methyl-4-cyclopentenone in a yield of 80 %.

後処理

  1. additionwere charged
  2. customwas consumed
  3. additionThe reaction mixture was treated as in Example 1

出典と根拠

ORDレコード
ord-627baeafa549496b8524eb7a461d6c84
出典データセット
uspto-grants-1990_11
特許番号
US04970345

反応ノート

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