Ethyl bromoacetate → Ethyl [(4-Chlorophenyl)thio]acetate
反応式
[C:1]1([S:7][CH2:8][C:9]([O:11][CH2:12][CH3:13])=[O:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.BrCC(OCC)=O.[Cl:21]C1C=CC(S)=CC=1>CC[O-].[Na+]>[Cl:21][C:4]1[CH:5]=[CH:6][C:1]([S:7][CH2:8][C:9]([O:11][CH2:12][CH3:13])=[O:10])=[CH:2][CH:3]=1参加物
5
実験手順
The procedure is as in Example 2 for the preparation of ethyl (phenylthio)acetate starting with ethyl bromoacetate (16.7 g), a 2M ethanolic solution of sodium ethylate (50 cc) and 4-chlorothiophenol (14.5 g). Ethyl (4-chlorophenylthio)acetate (20.7 g) is thereby obtained, and is used in the crude state in the subsequent phases.
出典と根拠
- ORDレコード
- ord-909f2f893d9a4ddd9a4554cc6552fef6
- 出典データセット
- uspto-grants-1990_11
- 特許番号
- US04971979
反応ノート
読み込み中…