Benzyl 4-Hydroxybenzoate → Benzoic acid, 4-(phenylmethoxy)-, phenylmethyl ester

HRID 1074295

反応式

HRID 1074295 の反応式
OC1C=CC(C([O-])=O)=CC=1.[Na+].[CH2:12](Cl)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1.C1(C)C(C)=CC=CC=1.[OH:28][C:29]1[CH:44]=[CH:43][C:32]([C:33]([O:35][CH2:36][C:37]2[CH:42]=[CH:41][CH:40]=[CH:39][CH:38]=2)=[O:34])=[CH:31][CH:30]=1>[Cl-].C([N+](CCCC)(CCCC)CCCC)CCC.C(C(C)=O)C>[CH2:12]([O:28][C:29]1[CH:44]=[CH:43][C:32]([C:33]([O:35][CH2:36][C:37]2[CH:42]=[CH:41][CH:40]=[CH:39][CH:38]=2)=[O:34])=[CH:31][CH:30]=1)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

参加物

7

反応物 4

HCID 7180Benzyl 4-HydroxybenzoateHCID 7237O-XyleneHCID 7503Benzyl ChlorideHCID 16219477Sodium 4-hydroxybenzoate

生成物 1

HCID 91863Benzoic acid, 4-(phenylmethoxy)-, phenylmethyl ester収率 73%

試薬・触媒・溶媒 2

HCID 70681Tetrabutylammonium Chloride触媒HCID 6569Methyl Ethyl Ketone溶媒

実験手順

Sodium p-hydroxybenzoate (64 g) and 51 g of benzyl chloride were added to 300 g of xylene, and 1.3 g of tetrabutyl ammonium chloride as a phase transfer catalyst and 2 g of methyl ethyl ketone were added. The mixture was refluxed for 8 hours Benzyl p-hydroxybenzoate was obtained in a yield of 73%, and the ratio of benzyl p-benzyloxybenzoate formed was 13%.

後処理

  1. additionwere added
  2. customwas obtained in a yield of 73%

出典と根拠

ORDレコード
ord-134e8fd2534d44edb64b6d218002ce3e
出典データセット
uspto-grants-1990_11
特許番号
US04973737

関連ノート

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