Hydrochloric Acid → HCID 20496918、化合物

HRID 1074480ノート

反応式

HRID 1074480 の反応式
[OH:1][C:2]1[CH:7]=[C:6]([C:8]([CH3:16])([CH3:15])[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14])[CH:5]=[CH:4][C:3]=1[CH:17]1[CH2:22][CH2:21][CH2:20][C:19](=[O:23])[CH2:18]1.[C:24](OC(=O)C)(=[O:26])[CH3:25].Cl>N1C=CC=CC=1>[C:24]([O:1][C:2]1[CH:7]=[C:6]([C:8]([CH3:16])([CH3:15])[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14])[CH:5]=[CH:4][C:3]=1[CH:17]1[CH2:22][CH2:21][CH2:20][C:19](=[O:23])[CH2:18]1)(=[O:26])[CH3:25]

参加物

5

反応物 3

HCID 313Hydrochloric AcidHCID 7918Acetic AnhydrideHCID 127881913-[2-Hydroxy-4-(2-methyloctan-2-yl)phenyl]cyclohexan-1-one

生成物 1

HCID 20496918HCID 20496918、化合物

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

実験手順

A solution of 2.0 g of 3-[2-hydroxy-4-(1,1-dimethylheptyl)phenyl]cyclohexanone in 15 ml of pyridine is treated at 10° C. with 10 ml acetic anhydride and the mixture stirred for 18 hours under nitrogen. It is then poured onto ice/water and acidified with dilute hydrochloric acid. The acidified mixture is extracted with ethyl acetate (2×100 ml), the extracts combined, washed with brine and dried (MgSO4). Evaporation under reduced pressure give the title product as an oil.

後処理

  1. additionIt is then poured onto ice/water
  2. extractionThe acidified mixture is extracted with ethyl acetate (2×100 ml)
  3. washwashed with brine
  4. dry with materialdried (MgSO4)
  5. customEvaporation under reduced pressure

出典と根拠

ORDレコード
ord-b54a4a25972c413586f30daf6898b3b2
出典データセット
uspto-grants-1983_07
特許番号
US04391827

反応ノート

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