反応式
[C:1]1([CH:7]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[C:8](=[O:10])[CH3:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Br:17]CC(=O)C(C1C=CC=CC=1)C1C=CC=CC=1.[NH:34]1[CH2:39][CH2:38][CH2:37][NH:36][C:35]1=[S:40]>CC(C)=O>[BrH:17].[C:11]1([CH:7]([C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)[C:8]2([OH:10])[N:36]3[CH2:37][CH2:38][CH2:39][N:34]=[C:35]3[S:40][CH2:9]2)[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=1参加物
5
実験手順
A 2.1 g. portion of 1,1-diphenyl-2-propanone is converted to 1-bromo-3,3-diphenyl-2-propanone by the procedure of Example 22. The 1-bromo-3,3-diphenyl-2-propanone is dissolved in 15 ml. of acetone and added to a boiling mixture of 0.80 g. of tetrahydro-2-pyrimidinethione in 70 ml. of acetone. This mixture is allowed to stand for 48 hours and the resulting solid is collected by filtration, giving the desired product, m.p. 196°-198° C.
後処理
- filtrationthe resulting solid is collected by filtration
出典と根拠
- ORDレコード
- ord-efa704cb1c0d421ba273e5a225d15ade
- 出典データセット
- uspto-grants-1983_07
- 特許番号
- US04393004
関連ノート
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