Methyl iodide → HCID 20495945、化合物

反応式

CI.[CH3:3][O:4][C:5]1[C:10]([CH:11]2[CH2:15][CH2:14][CH2:13][O:12]2)=[C:9]([CH3:16])[C:8]([O:17][CH3:18])=[C:7]([O:19][CH3:20])[C:6]=1[O:21][CH3:22]>>[CH3:3][O:4][C:5]1[C:10]([CH2:11][CH2:15][CH2:14][CH2:13][OH:12])=[C:9]([CH3:16])[C:8]([O:17][CH3:18])=[C:7]([O:19][CH3:20])[C:6]=1[O:21][CH3:22]

参加物

反応物 2

HCID 6328Methyl iodide

HCID 13187542HCID 13187542、化合物

生成物 1

HCID 20495945HCID 20495945、化合物収率 99%

実験手順

By the same procedure as described in Reference Example 58, 2,3-dimethoxy-5-methyl-6-(tetrahydrofur-2-yl)-1,4-benzohydroquinone (27 g, 0.106 mole) was methylated with methyl iodide, thereby being derived into 1,2,3,4-tetramethoxy-5-methyl-6-(tetrahydrofur-2-yl)benzene (28.5 g, 98%, bp1.0 135° to 138° C.). The catalytic reduction of the compound afforded 1,2,3,4-tetramethoxy-5-methyl-6-(4-hydroxybutyl)benzene (28.2 g, 99%, oily substance).

出典と根拠

ORDレコード: ord-33f482d33825431a97e9e86ebf99486b
出典データセット: uspto-grants-1983_07
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04393075

反応ノート

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