Water → 4-Chloro-6-aminobenzimidazolone
反応式
[N+:1]([C:4]1[CH:10]=[C:9]([N+:11]([O-])=O)[CH:8]=[C:7]([Cl:14])[C:5]=1[NH2:6])([O-])=O.[Se].[OH2:16].[CH2:17](N(CC)CC)C>O1CCCC1>[Cl:14][C:7]1[C:5]2[C:4](=[N:1][C:17](=[O:16])[N:6]=2)[CH:10]=[C:9]([NH2:11])[CH:8]=1参加物
6
反応条件
- 温度
- 80 °C
実験手順
2,4-Dinitro-6-chloroaniline 2.7 g (12.5 m moles), selenium 1.98 g (25.0 m moles), water 1.6 ml (89 m moles), triethylamine 5.0 g (50 m moles) and tetrahydrofuran 100 ml were placed in a 200-ml capacity autoclave, and stirred at a temperature of 80° C. for five hours under carbon monoxide of 20 Kg/cm2. The reaction mixture obtained was worked up in the same manner as in EXAMPLE 1, to provide 4-chloro-6 -aminobenzimidazolone in 84% yield.
後処理
- customThe reaction mixture obtained
出典と根拠
- ORDレコード
- ord-e5adb9b5df6e4e2b89c34407576fa6c0
- 出典データセット
- uspto-grants-1983_07
- 特許番号
- US04393216
反応ノート
読み込み中…