m-Chloroperbenzoic acid → 2-[(2,5-Dimethylphenyl)methylsulfonyl]-4-methylpyridine 1-oxide

反応式

[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([CH3:8])=[CH:4][C:3]=1[CH:9]([S:11][C:12]1[CH:17]=[C:16]([CH3:18])[CH:15]=[CH:14][N+:13]=1[O-:19])C.C1C=C(Cl)C=C(C(OO)=[O:28])C=1.C(O)C.[OH2:34]>>[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([CH3:8])=[CH:4][C:3]=1[CH2:9][S:11]([C:12]1[CH:17]=[C:16]([CH3:18])[CH:15]=[CH:14][N+:13]=1[O-:19])(=[O:28])=[O:34]

参加物

反応物 3

HCID 70297m-Chloroperbenzoic acid

HCID 13178742HCID 13178742、化合物

HCID 19096565Water ethanol

生成物 1

HCID 131787442-[(2,5-Dimethylphenyl)methylsulfonyl]-4-methylpyridine 1-oxide

実験手順

The sulfide compound (0.006 mole) is oxidized with MCPBA (0.014 mol) and is isolated in the manner described in Example 1. Yield 62% of theory. Melting point 156°-158° C. from ethanol/water (80/20 v/v) I.R. N→O 1275 cm-1, SO2 1135, 1310 cm-1.