Sodium Hydroxide → HCID 178512718、化合物

反応式

C[O:2][C:3]1[C:7](OC)=[N:6][S:5](=[O:11])(=[O:10])[N:4]=1.[NH:12]([C:16]1[S:17][CH:18]=[C:19]([CH2:21][S:22][CH2:23][CH2:24][NH2:25])[N:20]=1)[C:13]([NH2:15])=[NH:14].N(C1SC=C(CSCCNC2C(OC)=NSN=2)N=1)C(N)=N.[OH-].[Na+]>>[NH:12]([C:16]1[S:17][CH:18]=[C:19]([CH2:21][S:22][CH2:23][CH2:24][NH:25][C:7]2[C:3]([OH:2])=[N:4][S:5](=[O:11])(=[O:10])[N:6]=2)[N:20]=1)[C:13]([NH2:15])=[NH:14]

参加物

反応物 4

HCID 14798Sodium Hydroxide

HCID 122305383,4-Dimethoxy-1,2,5-thiadiazole 1,1-dioxide

HCID 1784943233-{2-[(2-Guanidinothiazol-4-yl)methylthio]ethylamino}-4-methoxy-1,2,5-thiadiazole

HCID 1785127232-[4-(2-Aminoethylsulfanylmethyl)-1,3-thiazol-2-yl]guanidine

生成物 1

HCID 178512718HCID 178512718、化合物

実験手順

When 3,4-dimethoxy-1,2,5-thiadiazole 1,1-dioxide is reacted with one equivalent of 2-[(2-guanidinothiazol-4-yl)methylthio]ethylamine and the resultant 3-{2-[(2-guanidinothiazol-4-yl)methylthio]ethylamino}-4-methoxy-1,2,5-thiadiazole, 1,1-dioxide is reacted with sodium hydroxide according to the procedure described in Example 17, Step B, the title compound is produced.